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MFI2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P08582
Clone Names 100623025
Additional Information
Gene ID 4241
Other Names Melanotransferrin, Melanoma-associated antigen p97, CD228, MFI2, MAP97
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MELTF (HGNC:7037)
Synonyms MAP97, MFI2
Function Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Cellular Location [Isoform 1]: Cell membrane; Lipid-anchor, GPI- anchor
Tissue Location Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a cell-surfaceglycoprotein found on melanoma cells. The protein shares sequencesimilarity and iron-binding properties with members of thetransferrin superfamily. The importance of the iron bindingfunction has not yet been identified. This gene resides in the sameregion of chromosome 3 as members of the transferrin superfamily.Alternative splicing results in two transcript variants. [providedby RefSeq].

References

Wang, M., et al. J. Biol. Chem. 284(48):33377-33383(2009)Farnaud, S., et al. Int. J. Biochem. Cell Biol. 40(12):2739-2745(2008)Suryo Rahmanto, Y., et al. Carcinogenesis 28(10):2172-2183(2007)Suryo Rahmanto, Y., et al. Oncogene 26(42):6113-6124(2007)Michaud-Levesque, J., et al. Biol. Chem. 388(7):747-754(2007)

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$ 277.78
Cat# BP19007b
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