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PMM2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O15305
Clone Names 100623033
Additional Information
Gene ID 5373
Other Names Phosphomannomutase 2, PMM 2, PMM2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PMM2
Function Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
Cellular Location Cytoplasm.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene catalyzes theisomerization of mannose 6-phosphate to mannose 1-phosphate, whichis a precursor to GDP-mannose necessary for the synthesis ofdolichol-P-oligosaccharides. Mutations in this gene have been shownto cause defects in glycoprotein biosynthesis, which manifests ascarbohydrate-deficient glycoprotein syndrome type I. [provided byRefSeq].

References

Vega, A.I., et al. Hum. Mutat. 30(5):795-803(2009)Coman, D., et al. Am. J. Med. Genet. A 146(3):389-392(2008)Vermeer, S., et al. J. Neurol. 254(10):1356-1358(2007)Coman, D., et al. J Clin Neurosci 14(7):668-672(2007)Schollen, E., et al. Mol. Genet. Metab. 90(4):408-413(2007)

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$ 277.78
Cat# BP19008b
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