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TBX4 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P57082
Clone Names 110808026
Additional Information
Gene ID 9496
Other Names T-box transcription factor TBX4, T-box protein 4, TBX4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX4
Function Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Research Areas
Citations (0)
citation

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Background

This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This gene is the human homolog of mouseTbx4, which is closely linked to Tbx2 on mouse chromosome 11.Similarly this gene, like TBX2, maps to human chromosome 17.Expression studies in mouse and chicken show that Tbx4 is expressedin developing hindlimb, but not in forelimb buds, suggesting a rolefor this gene in regulating limb development and specification oflimb identity.

References

Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)

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$ 277.78
Cat# BP19015a
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