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PAIP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H074
Clone Names 110901024
Peptide ID 110901024
Additional Information
Gene ID 10605
Other Names Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1, PAIP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAIP1
Function Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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The protein encoded by this gene interacts withpoly(A)-binding protein and with the cap-binding complex eIF4A. Itis involved in translational initiation and protein biosynthesis.Overexpression of this gene in COS7 cells stimulates translation.Alternative splicing occurs at this locus and three transcriptvariants encoding three distinct isoforms have been identified.


Kanaan, A.S., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (PT 10), 1060-1064 (2009) :Martineau, Y., et al. Mol. Cell. Biol. 28(21):6658-6667(2008)Fortna, A., et al. PLoS Biol. 2 (7), E207 (2004) :Roy, G., et al. Mol. Cell. Biol. 22(11):3769-3782(2002)Deo, R.C., et al. Proc. Natl. Acad. Sci. U.S.A. 98(8):4414-4419(2001)

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$ 80.00
Cat# BP19021a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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