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WHSC1L1 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BZ95
Clone Names 5041105
Additional Information
Gene ID 54904
Other Names Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing protein 3, Protein whistle, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, Wolf-Hirschhorn syndrome candidate 1-like protein 1, WHSC1-like protein 1, WHSC1L1, NSD3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1904a was selected from the C-term region of human WHSC1L1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NSD3 (HGNC:12767)
Synonyms WHSC1L1
Function Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.
Cellular Location Nucleus. Chromosome.
Tissue Location Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung
Research Areas
Citations (0)
citation

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Background

The gene for WHSC1L1 is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined.

References

Angrand, P.O., et al., Genomics 74(1):79-88 (2001).Stec, I., et al., FEBS Lett. 473(1):1-5 (2000).Stec, I., et al., Genomics 76 (1-3), 5-8 (2001) (): ().

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$ 277.78
Cat# BP1904a
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