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TIMM50 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q3ZCQ8 |
|---|---|
| Clone Names | 110617100 |
| Gene ID | 92609 |
|---|---|
| Other Names | Mitochondrial import inner membrane translocase subunit TIM50, TIMM50, TIM50 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TIMM50 |
|---|---|
| Synonyms | TIM50 |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
| Tissue Location | Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Xu, H., et al. BMC Cell Biol. 6 (1), 29 (2005) :Guo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)Yuryev, A., et al. Genomics 81(2):112-125(2003)Yamamoto, H., et al. Cell 111(4):519-528(2002)
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