GKN1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NS71 |
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Clone Names | 110617243 |
Gene ID | 56287 |
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Other Names | Gastrokine-1, 18 kDa antrum mucosa protein, AMP-18, Protein CA11, GKN1, AMP18, CA11 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GKN1 |
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Synonyms | AMP18, CA11 |
Function | Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium. |
Cellular Location | Secreted. Cytoplasmic granule. Golgi apparatus. Note=Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus. |
Tissue Location | Expressed in stomach (at protein level). No expression is detected in cancer tissue or gastric cancer cell lines |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is found to bedown-regulated in human gastric cancer tissue as compared to normalgastric mucosa.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Broderick, P., et al. Cancer Res. 69(16):6633-6641(2009)Nardone, G., et al. Cancer Biol. Ther. 7(12):1890-1895(2008)Moss, S.F., et al. Clin. Cancer Res. 14(13):4161-4167(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)
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