|Other Names||Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, Solute carrier family 25 member 11, SLC25A11, SLC20A4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The oxoglutarate/malate carrier transports 2-oxoglutarateacross the inner membranes of mitochondria in an electroneutralexchange for malate or other dicarboxylic acids (summarized byIacobazzi et al., 1992 [PubMed 1457818]).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Kabe, Y., et al. J. Biol. Chem. 281(42):31729-31735(2006)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Coll, O., et al. Hepatology 38(3):692-702(2003)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.