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RFC1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P35251
Clone Names 90713180
Peptide ID 90713180
Additional Information
Gene ID 5981
Other Names Replication factor C subunit 1, Activator 1 140 kDa subunit, A1 140 kDa subunit, Activator 1 large subunit, Activator 1 subunit 1, DNA-binding protein PO-GA, Replication factor C 140 kDa subunit, RF-C 140 kDa subunit, RFC140, Replication factor C large subunit, RFC1, RFC140
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RFC1
Synonyms RFC140
Function The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA.
Cellular Location Nucleus.
Tissue Location Wide tissue distribution. Undetectable in placental tissue
Research Areas
Citations (0)

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The protein encoded by this gene is the large subunit ofreplication factor C, which is a five subunit DNA polymeraseaccessory protein. Replication factor C is a DNA-dependent ATPasethat is required for eukaryotic DNA replication and repair. Theprotein acts as an activator of DNA polymerases, binds to the 3'end of primers, and promotes coordinated synthesis of both strands.It also may have a role in telomere stability. [provided byRefSeq].


Overmeer, R.M., et al. Mol. Cell. Biol. 30(20):4828-4839(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Arora, M., et al. Leukemia 24(8):1470-1475(2010)Galbiatti, A.L., et al. Mol. Biol. Rep. (2010) In press :Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 80.00
Cat# BP19110a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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