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PES1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00541
Clone Names 100517064
Peptide ID 100517064
Additional Information
Gene ID 23481
Other Names Pescadillo homolog {ECO:0000255|HAMAP-Rule:MF_03028}, PES1 {ECO:0000255|HAMAP-Rule:MF_03028}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PES1 {ECO:0000255|HAMAP-Rule:MF_03028}
Function Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Cellular Location Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli {ECO:0000255|HAMAP-Rule:MF_03028}
Tissue Location Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin
Research Areas
Citations (0)

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This gene encodes a protein that is abnormally elevated inmalignant tumors of astrocytic origin. It is a strongly conservedgene containing a BRCT domain that is essential for the activity ofthis gene product. The gene plays a crucial role in cellproliferation and may be necessary for oncogenic transformation andtumor progression.


Zhang, J., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(12):991-997(2009)Li, J., et al. Cancer Sci. 100(12):2255-2260(2009)Rikova, K., et al. Cell 131(6):1190-1203(2007)Rohrmoser, M., et al. Mol. Cell. Biol. 27(10):3682-3694(2007)Grimm, T., et al. Nucleic Acids Res. 34(10):3030-3043(2006)

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$ 80.00
Cat# BP19122b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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