|Other Names||Relaxin-3 receptor 1, RLN3 receptor 1, G protein-coupled receptor SALPR, G-protein coupled receptor GPCR135, Relaxin family peptide receptor 3, Somatostatin- and angiotensin-like peptide receptor, RXFP3, RLN3R1, SALPR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis|
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Provided below are standard protocols that you may find useful for product applications.
RXFP3 is a receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Huang, Y.W., et al. Gynecol. Oncol. 117(2):239-247(2010)van der Westhuizen, E.T., et al. Mol. Pharmacol. 77(5):759-772(2010)Hossain, M.A., et al. Chem Biol Drug Des 73(1):46-52(2009)Zhu, J., et al. Eur. J. Pharmacol. 590 (1-3), 43-52 (2008) :Hossain, M.A., et al. J. Biol. Chem. 283(25):17287-17297(2008)
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