|Other Names||Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich protein, BCL2L12, BPR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle|
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The protein encoded by this gene belongs to the BCL-2protein family. BCL-2 family members form hetero- or homodimers andact as anti- or pro-apoptotic regulators that are involved in awide variety of cellular activities. This protein contains a Bcl-2homology domain 2 (BH2). The function of this gene has not yet beendetermined. Two alternatively spliced transcript variants of thisgene encoding distinct isoforms have been reported. [provided byRefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Florou, D., et al. Biochem. Biophys. Res. Commun. 391(1):214-218(2010)Hong, Y., et al. Mol. Cell. Biochem. 333 (1-2), 323-330 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Thomadaki, H., et al. Ann. N. Y. Acad. Sci. 1171, 276-283 (2009) :
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