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DRG2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P55039 |
|---|---|
| Clone Names | 110826107 |
| Gene ID | 1819 |
|---|---|
| Other Names | Developmentally-regulated GTP-binding protein 2, DRG-2, DRG2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DRG2 {ECO:0000303|PubMed:29915238, ECO:0000312|HGNC:HGNC:3030} |
|---|---|
| Function | Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes |
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Provided below are standard protocols that you may find useful for product applications.
Background
The DRG2 gene encodes the developmentally regulatedGTP-binding protein 2, a name derived from the fact that it sharessignificant similarity to known GTP-binding proteins. DRG2 wasidentified because it is expressed in normal fibroblasts but not inSV40-transformed fibroblasts. Read-through transcripts containingthis gene and a downstream gene have been identified, but they arenot thought to encode a fusion protein. This gene is located withinthe Smith-Magenis syndrome region on chromosome 17. [provided byRefSeq].
References
Song, H., et al. J. Biochem. 135(3):331-335(2004)Bi, W., et al. Genome Res. 12(5):713-728(2002)Li, B., et al. Biochim. Biophys. Acta 1491 (1-3), 196-204 (2000) :Vlangos, C.N., et al. Cytogenet. Cell Genet. 88 (3-4), 283-285 (2000) :Liang, Y., et al. Genomics 61(3):243-258(1999)
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