|Other Names||Ammonium transporter Rh type C, Rh glycoprotein kidney, Rhesus blood group family type C glycoprotein, Rh family type C glycoprotein, Rh type C glycoprotein, Tumor-related protein DRC2, RHCG, C15orf6, CDRC2, PDRC2, RHGK|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C15orf6, CDRC2, PDRC2, RHGK|
|Function||Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.|
|Cellular Location||Apical cell membrane; Multi- pass membrane protein. Note=Also detected at the basolateral membrane and in subapical vesicles.|
|Tissue Location||Expressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). According to PubMed:11062476, specifically expressed in kidney.|
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RHCG functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Gruswitz, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(21):9638-9643(2010)Mouro-Chanteloup, I., et al. PLoS ONE 5 (1), E8921 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Han, K.H., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 297 (1), L153-L163 (2009) :
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