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XYLT2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H1B5
Clone Names 100318278
Peptide ID 100318278
Additional Information
Gene ID 64132
Other Names Xylosyltransferase 2, Peptide O-xylosyltransferase 1, Xylosyltransferase II, XT-II, XylT-II, XYLT2, XT2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name XYLT2
Synonyms XT2
Function Involved in the formation of heparan sulfate and chondroitin sulfate proteoglycans (PubMed:26027496). Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Widely expressed. Expressed at higher level in kidney and pancreas.
Research Areas
Citations (0)

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The protein encoded by this gene is an isoform ofxylosyltransferase, which belongs to a family ofglycosyltransferases. This enzyme transfers xylose from UDP-xyloseto specific serine residues of the core protein and initiates thebiosynthesis of glycosaminoglycan chains in proteoglycans includingchondroitin sulfate, heparan sulfate, heparin and dermatan sulfate.The enzyme activity, which is increased in scleroderma patients, isa diagnostic marker for the determination of sclerotic activity insystemic sclerosis.


Condac, E., et al. Glycobiology 19(8):829-833(2009)Casanova, J.C., et al. Biochem. Biophys. Res. Commun. 383(1):4-10(2009)Ponighaus, C., et al. Am. J. Hypertens. 22(4):432-436(2009)Ambrosius, M., et al. Clin. Biochem. 42 (1-2), 1-4 (2009) :Hendig, D., et al. Clin. Chim. Acta 398 (1-2), 90-94 (2008) :

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$ 80.00
Cat# BP19159a
Availability: In Stock
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