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TIMM10 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P62072
Clone Names 100405042
Additional Information
Gene ID 26519
Other Names Mitochondrial import inner membrane translocase subunit Tim10, TIMM10, TIM10
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMM10
Synonyms TIM10
Function Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Cellular Location Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side
Tissue Location Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
Research Areas
Citations (0)
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Background

TIMM10 belongs to a family of evolutionarily conservedproteins that are organized in heterooligomeric complexes in themitochondrial intermembrane space. These proteins mediate theimport and insertion of hydrophobic membrane proteins into themitochondrial inner membrane.

References

Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Carey, K.A., et al. Pathol. Int. 56(5):246-255(2006)Webb, C.T., et al. Mol. Cell 21(1):123-133(2006)Muhlenbein, N., et al. J. Biol. Chem. 279(14):13540-13546(2004)Allen, S., et al. J. Biol. Chem. 278(40):38505-38513(2003)

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$ 277.78
Cat# BP19169c
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