|Other Names||Transcobalamin-1, TC-1, Haptocorrin, HC, Protein R, Transcobalamin I, TC I, TCI, TCN1, TC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.|
|Tissue Location||Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the vitamin B12-bindingprotein family. This family of proteins, alternatively referred toas R binders, is expressed in various tissues and secretions. Thisprotein is a major constituent of secondary granules in neutrophilsand facilitates the transport of cobalamin into cells. [provided byRefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Garrod, M.G., et al. Eur J Clin Nutr 64(5):503-509(2010)Matteini, A.M., et al. J Nutr Health Aging 14(1):73-77(2010)McGeachie, M., et al. Circulation 120(24):2448-2454(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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