|Other Names||Sorting and assembly machinery component 50 homolog, Transformation-related gene 3 protein, TRG-3, SAMM50, SAM50|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be required for the assembly pathway of mitochondrial outer membrane proteins.|
|Cellular Location||Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm|
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Provided below are standard protocols that you may find useful for product applications.
SAMM50 is a component of the sorting and assemblymachinery (SAM) complex of the outer mitochondrial membrane. TheSAM complex has a role in integrating beta-barrel proteins into theouter mitochondrial membrane (Humphries et al., 2005 [PubMed15644312]).
Bailey, S.D., et al. Diabetes Care (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Yuan, X., et al. Am. J. Hum. Genet. 83(4):520-528(2008)Xie, J., et al. FEBS Lett. 581(18):3545-3549(2007)
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