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Mouse Dcc Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P70211
Clone Names 110919035
Peptide ID 110919035
Additional Information
Gene ID 13176
Other Names Netrin receptor DCC, Tumor suppressor protein DCC, Dcc
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dcc
Function Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location In the embryo, expressed at high levels in the developing brain and neural tube. In adult, highly expressed in brain with very low levels found in testis, heart and thymus Isoform C is expressed only in the embryo
Research Areas
Citations (0)

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Background

Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

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$ 80.00
Cat# BP19225b
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