|Other Names||Mitochondrial fission factor, MFF, C2orf33|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle|
|Tissue Location||Highly expressed in heart, kidney, liver, brain, muscle, and stomach.|
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Provided below are standard protocols that you may find useful for product applications.
MFF plays a role in mitochondrial and peroxisomal fission.
Gandre-Babbe, S., et al. Mol. Biol. Cell 19(6):2402-2412(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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