|Other Names||Solute carrier family 25 member 36, SLC25A36|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10- phenanthroline, tannic acid, and mercurials (mercury dichloride, Mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
|Tissue Location||Expressed at moderate level.|
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Provided below are standard protocols that you may find useful for product applications.
SLC25A36 belongs to the mitochondrial carrier family. It contains 3 Solcar repeats and has three isoforms.
Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)Stelzl, U., et al. Cell 122(6):957-968(2005)Laganiere, J., et al. Mol. Endocrinol. 19(6):1584-1592(2005)Hildyard, J.C., et al. Biochem. J. 374 (PT 3), 607-611 (2003) :
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