SLC25A36 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96CQ1 |
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Clone Names | 110808023 |
Gene ID | 55186 |
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Other Names | Solute carrier family 25 member 36, SLC25A36 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC25A36 |
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Function | Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Selectively transports cytosine, guanosine, inosine and uridine (deoxy)nucleoside mono-, di-, and triphosphates by antiport mechanism. Catalyzes uniport at much lower rate (PubMed:25320081). May import (deoxy)nucleoside triphosphates in exchange for intramitochondrial (deoxy)nucleoside mono- and diphosphates, thus providing precursors necessary for de novo synthesis of mitochondrial DNA and RNA while exporting products of their catabolism (PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration. |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed at moderate level. Expressed most strongly in pancreas (PubMed:34971397). |
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC25A36 belongs to the mitochondrial carrier family. It contains 3 Solcar repeats and has three isoforms.
References
Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)Stelzl, U., et al. Cell 122(6):957-968(2005)Laganiere, J., et al. Mol. Endocrinol. 19(6):1584-1592(2005)Hildyard, J.C., et al. Biochem. J. 374 (PT 3), 607-611 (2003) :
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