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BNIP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q12981
Clone Names 100409005
Peptide ID 100409005
Additional Information
Gene ID 662
Other Names Vesicle transport protein SEC20, BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, Transformation-related gene 8 protein, TRG-8, BNIP1, NIP1, SEC20L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BNIP1
Synonyms NIP1, SEC20L
Function SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy.
Cellular Location Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein
Tissue Location Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine
Research Areas
Citations (0)

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Background

This gene is a member of the BCL2/adenovirus E1B 19kd-interacting protein (BNIP) family. It interacts with the E1B 19kDa protein which is responsible for the protection ofvirally-induced cell death, as well as E1B 19 kDa-like sequences ofBCL2, also an apoptotic protector. Alternative splicing of thisgene results in four protein products with identical N- andC-termini.

References

Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Nakajima, K., et al. EMBO J. 23(16):3216-3226(2004)Zhang, H., et al. FEBS Lett. 448(1):23-27(1999)Kataoka, N., et al. Nucleic Acids Res. 23(18):3638-3641(1995)

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$ 80.00
Cat# BP19321a
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