|Other Names||Tripartite motif-containing protein 29, Ataxia telangiectasia group D-associated protein, TRIM29, ATDC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.|
|Cellular Location||Cytoplasm. Note=Colocalizes with intermediate filaments|
|Tissue Location||Expressed in placenta, prostate and thymus.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the TRIMprotein family. It has multiple zinc finger motifs and a leucinezipper motif. It has been proposed to form homo- or heterodimerswhich are involved in nucleic acid binding. Thus, it may act as atranscriptional regulatory factor involved in carcinogenesis and/ordifferentiation. It may also function in the suppression ofradiosensitivity since it is associated with ataxia telangiectasiaphenotype.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Yuan, Z., et al. Mol. Cell. Biol. 30(12):3004-3015(2010)Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)Bertrand-Vallery, V., et al. PLoS ONE 5 (5), E10462 (2010) :Ring, B.Z., et al. Mod. Pathol. 22(8):1032-1043(2009)
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