CAPNS2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96L46 |
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Clone Names | 100507104 |
Gene ID | 84290 |
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Other Names | Calpain small subunit 2, CSS2, Calcium-dependent protease small subunit 2, CAPNS2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CAPNS2 |
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Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity. |
Cellular Location | Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon calcium binding. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Ma, H., et al. Curr. Eye Res. 29 (4-5), 337-347 (2004) :Schad, E., et al. Biochem. J. 362 (PT 2), 383-388 (2002) :
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