|Other Names||Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Fan, J., et al. J. Neurochem. 115(4):1045-1056(2010)Ohno, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(34):15252-15257(2010)Jin, S.X., et al. PLoS ONE 5 (7), E11732 (2010) :Tang, T.T., et al. Proc. Natl. Acad. Sci. U.S.A. 106(50):21395-21400(2009)Taniguchi, S., et al. EMBO J. 28(23):3717-3729(2009)
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