|Other Names||Phosphatidylethanolamine-binding protein 4, PEBP-4, hPEBP4, Protein cousin-of-RKIP 1, PEBP4, CORK1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization.|
|Tissue Location||Ubiquitously expressed. Highly expressed in tumor cells.|
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Provided below are standard protocols that you may find useful for product applications.
The phosphatidylethanolamine (PE)-binding proteins,including PEBP4, are an evolutionarily conserved family of proteinswith pivotal biologic functions, such as lipid binding andinhibition of serine proteases (Wang et al., 2004 [PubMed15302887]).
Liu, H., et al. J. Biol. Chem. 285(29):21934-21942(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Trynka, G., et al. Gut 58(8):1078-1083(2009)Garcia, R., et al. EMBO Rep. 10(3):278-284(2009)Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008)
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