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SMG5 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UPR3
Clone Names 100517139
Peptide ID 100517139
Additional Information
Gene ID 23381
Other Names Protein SMG5, EST1-like protein B, LPTS-RP1, LPTS-interacting protein, SMG-5 homolog, hSMG-5, SMG5, EST1B, KIAA1089
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMG5
Synonyms EST1B, KIAA1089
Function Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm Detected in cytoplasmic mRNA decay bodies
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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SMG5 is involved in nonsense-mediated mRNA decay (Ohnishiet al., 2003 [PubMed 14636577]).


Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)Glavan, F., et al. EMBO J. 25(21):5117-5125(2006)Lee, H., et al. Mol. Cell. Biol. 26(14):5259-5269(2006)Azzalin, C.M., et al. Curr. Biol. 16(4):433-439(2006)Unterholzner, L., et al. Mol. Cell 16(4):587-596(2004)

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$ 80.00
Cat# BP19361b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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