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XRCC2 Antibody(N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O43543
Clone Names 100430256
Peptide ID 100430256
Additional Information
Gene ID 7516
Other Names DNA repair protein XRCC2, X-ray repair cross-complementing protein 2, XRCC2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name XRCC2
Function Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2- dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Cellular Location Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Research Areas
Citations (0)

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This gene encodes a member of the RecA/Rad51-relatedprotein family that participates in homologous recombination tomaintain chromosome stability and repair DNA damage. This gene isinvolved in the repair of DNA double-strand breaks by homologousrecombination and it functionally complements Chinese hamster irs1,a repair-deficient mutant that exhibits hypersensitivity to anumber of different DNA-damaging agents.


Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010)Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)

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$ 80.00
Cat# BP19368a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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