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RNF135 Antibody(C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8IUD6
Clone Names 110901112
Peptide ID 110901112
Additional Information
Gene ID 84282
Other Names E3 ubiquitin-protein ligase RNF135, 632-, RIG-I E3 ubiquitin ligase, REUL, RING finger protein 135, Riplet, RNF135
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF135
Function Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.
Cellular Location Cytoplasm.
Tissue Location Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung
Research Areas
Citations (0)

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The protein encoded by this gene contains a RING fingerdomain, a motif present in a variety of functionally distinctproteins and known to be involved in protein-protein andprotein-DNA interactions. This gene is located in a chromosomalregion known to be frequently deleted in patients withneurofibromatosis. Alternatively spliced transcript variantsencoding distinct isoforms have been reported. [provided byRefSeq].


Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :You, F., et al. Nat. Immunol. 10(12):1300-1308(2009)Visser, R., et al. Am. J. Med. Genet. A 149A (4), 806-808 (2009) :Oshiumi, H., et al. J. Biol. Chem. 284(2):807-817(2009)Gao, D., et al. PLoS ONE 4 (6), E5760 (2009) :

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$ 80.00
Cat# BP19376b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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