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MRPL24 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96A35
Clone Names 50908325
Additional Information
Gene ID 79590
Other Names 39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24, MRPL24
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1940a was selected from the N-term region of human MRPL24. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRPL24
Cellular Location Mitochondrion
Research Areas
Citations (0)
citation

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Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL24 is a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24).

References

Zhang, Z., et al., Genomics 81(5):468-480 (2003).O'Brien, T.W., et al., J. Biol. Chem. 275(24):18153-18159 (2000).Kenmochi, N., et al., Genomics 77 (1-2), 65-70 (2001).

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$ 277.78
Cat# BP1940a
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