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Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q02127 |
|---|---|
| Clone Names | 100712065 |
| Peptide ID | 100712065 |
| Gene ID | 1723 |
|---|---|
| Other Names | Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DHODH |
|---|---|
| Function | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene catalyzes the fourthenzymatic step, the ubiquinone-mediated oxidation of dihydroorotateto orotate, in de novo pyrimidine biosynthesis. This protein is amitochondrial protein located on the outer surface of the innermitochondrial membrane.
References
Hail, N. Jr., et al. Free Radic. Biol. Med. 49(1):109-116(2010)Ng, S.B., et al. Nat. Genet. 42(1):30-35(2010)Grabar, P.B., et al. Ann. Rheum. Dis. 68(8):1367-1368(2009)Pawlik, A., et al. Pharmacogenomics 10(2):303-309(2009)Anney, R.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1369-1378 (2008) :
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