DHODH Antibody(Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q02127 |
---|---|
Clone Names | 100712065 |
Gene ID | 1723 |
---|---|
Other Names | Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DHODH |
---|---|
Function | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway. |
Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene catalyzes the fourthenzymatic step, the ubiquinone-mediated oxidation of dihydroorotateto orotate, in de novo pyrimidine biosynthesis. This protein is amitochondrial protein located on the outer surface of the innermitochondrial membrane.
References
Hail, N. Jr., et al. Free Radic. Biol. Med. 49(1):109-116(2010)Ng, S.B., et al. Nat. Genet. 42(1):30-35(2010)Grabar, P.B., et al. Ann. Rheum. Dis. 68(8):1367-1368(2009)Pawlik, A., et al. Pharmacogenomics 10(2):303-309(2009)Anney, R.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1369-1378 (2008) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.