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Mouse Ephb6 Antibody(Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O08644 |
|---|---|
| Clone Names | 110316153 |
| Gene ID | 13848 |
|---|---|
| Other Names | Ephrin type-B receptor 6, MEP, Tyrosine-protein kinase-defective receptor EPH-6, Ephb6, Cekl |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Ephb6 |
|---|---|
| Synonyms | Cekl |
| Function | Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity). |
| Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted. |
| Tissue Location | High level in thymus, and brain. Very low levels of expression in kidney, lung, liver, bone marrow, skeletal muscle, spleen from 2 week old and adult mice, heart, testes and embryonic stem cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).
References
Islam, S., et al. Dig. Dis. Sci. 55(9):2478-2488(2010)Lieben, L., et al. Bone 47(2):301-308(2010)Mordan-McCombs, S., et al. J. Steroid Biochem. Mol. Biol. 121 (1-2), 368-371 (2010) :Zirzow, S., et al. Dev. Biol. 336(2):145-155(2009)Chou, S.J., et al. Nat. Neurosci. 12(11):1381-1389(2009)
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