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ZHX1 Antibody(C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UKY1
Clone Names 100712134
Peptide ID 100712134
Additional Information
Gene ID 11244
Other Names Zinc fingers and homeoboxes protein 1, ZHX1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZHX1
Function Acts as a transcriptional repressor. Increases DNMT3B- mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co- repressor proteins.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12237128, ECO:0000269|PubMed:17056598}. Note=Colocalized in the nucleus with DNMT3B
Tissue Location Ubiquitously expressed. Expressed in podocytes.
Research Areas
Citations (0)

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Background

The members of the zinc fingers and homeoboxes gene familyare nuclear homodimeric transcriptional repressors that interactwith the A subunit of nuclear factor-Y (NF-YA) and contain twoC2H2-type zinc fingers and five homeobox DNA-binding domains. Thisgene encodes member 1 of this gene family. In addition to forminghomodimers, this protein heterodimerizes with members 2 and 3 ofthe zinc fingers and homeoboxes family. Alternative splicingresults in multiple transcript variants encoding the same protein.

References

Wienk, H., et al. Biochemistry 48(21):4431-4439(2009)Rikova, K., et al. Cell 131(6):1190-1203(2007)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Kim, S.H., et al. Biochem. Biophys. Res. Commun. 355(2):318-323(2007)Liu, G., et al. J. Biol. Chem. 281(51):39681-39692(2006)

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$ 80.00
Cat# BP19424b
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