|Other Names||Syntaxin-11, STX11|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.|
|Cellular Location||Membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein|
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This gene encodes a member of the syntaxin family.Syntaxins have been implicated in the targeting and fusion ofintracellular transport vesicles. This family member may regulateprotein transport among late endosomes and the trans-Golgi network.Mutations in this gene have been associated with familialhemophagocytic lymphohistiocytosis.
Marsh, R.A., et al. Pediatr Blood Cancer 55(1):134-140(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Danielian, S., et al. J. Clin. Immunol. 30(2):330-337(2010)zur Stadt, U., et al. Am. J. Hum. Genet. 85(4):482-492(2009)Marcelin, G., et al. Mamm. Genome 20(3):131-139(2009)
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