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Cleavage stimulation factor 2 (CSTF2) Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P33240
Clone Names 50908330
Peptide ID 50908330
Additional Information
Gene ID 1478
Other Names Cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, CstF-64, CSTF2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1942a was selected from the N-term region of human CSTF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSTF2
Function One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity).
Cellular Location Nucleus. Note=Localized with DDX1 in cleavage bodies
Research Areas
Citations (0)

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CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.


Takagaki, Y., et al., Mol. Cell 2(6):761-771 (1998).Martincic, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95(19):11095-11100 (1998).Takagaki, Y., et al., Cell 87(5):941-952 (1996).Takagaki, Y., et al., Nature 372(6505):471-474 (1994).Takagaki, Y., et al., Proc. Natl. Acad. Sci. U.S.A. 89(4):1403-1407 (1992).

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$ 80.00
Cat# BP1942a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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