|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the peroxisomeproliferator-activated receptor (PPAR) subfamily of nuclearreceptors. PPARs form heterodimers with retinoid X receptors (RXRs)and these heterodimers regulate transcription of various genes.Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, andPPAR-gamma. The protein encoded by this gene is PPAR-gamma and is aregulator of adipocyte differentiation. Additionally, PPAR-gammahas been implicated in the pathology of numerous diseases includingobesity, diabetes, atherosclerosis and cancer. Alternativelyspliced transcript variants that encode different isoforms havebeen described.
Park, S.H., et al. J. Immunol. 185(9):5522-5530(2010)Waku, T., et al. EMBO J. 29(19):3395-3407(2010)Christopoulos, P., et al. Ann. N. Y. Acad. Sci. 1205, 185-191 (2010) :Sarzynski, M.A., et al. Int J Obes (Lond) (2010) In press :Chaia Kaippert, V., et al. Nutr Hosp 25(4):622-629(2010)
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