PLXDC1 Antibody(C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IUK5 |
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Clone Names | 100603056 |
Gene ID | 57125 |
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Other Names | Plexin domain-containing protein 1, Tumor endothelial marker 3, Tumor endothelial marker 7, PLXDC1, TEM3, TEM7 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PLXDC1 |
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Synonyms | TEM3, TEM7 |
Function | Plays a critical role in endothelial cell capillary morphogenesis. |
Cellular Location | Secreted [Isoform 2]: Secreted. [Isoform 4]: Cytoplasm. |
Tissue Location | Detected in urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a critical role in endothelial cell capillary morphogenesis.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Halder, C., et al. Anticancer Res. 29(11):4317-4322(2009)Yamaji, Y., et al. Invest. Ophthalmol. Vis. Sci. 49(7):3151-3157(2008)Fuchs, B., et al. Gene 399(2):137-143(2007)Nanda, A., et al. Cancer Res. 64(23):8507-8511(2004)
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