|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3 (By similarity).
Titz, B., et al. Oncogene 29(44):5895-5910(2010)Mashima, R., et al. Lab. Invest. 90(9):1357-1364(2010)Berger, A.H., et al. Nat. Genet. 42(3):216-223(2010)Warner, N., et al. FEBS J. 275(10):2561-2573(2008)Hosooka, T., et al. Nat. Med. 14(2):188-193(2008)
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