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PDCD2L Antibody(Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BRP1
Clone Names 100603327
Peptide ID 100603327
Additional Information
Other Names Programmed cell death protein 2-like, PDCD2L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDCD2L
Function Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase.
Tissue Location Higher expression in lung, colon, mammary gland, cervix, stomach and small intestine EMBL; AC008747; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AC092073; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC006146; AAH06146.1; -; mRNA CCDS; CCDS12438.1; - RefSeq; NP_115722.1; NM_032346.1 UniGene; Hs.515344; - ProteinModelPortal; Q9BRP1; - BioGrid; 124032; 22 IntAct; Q9BRP1; 5 STRING; 9606.ENSP00000246535; - iPTMnet; Q9BRP1; - PhosphoSitePlus; Q9BRP1; - BioMuta; PDCD2L; - DMDM; 74732907; - EPD; Q9BRP1; - MaxQB; Q9BRP1; - PaxDb; Q9BRP1; - PeptideAtlas; Q9BRP1; - PRIDE; Q9BRP1; - DNASU; 84306; - Ensembl; ENST00000246535; ENSP00000246535; ENSG00000126249 GeneID; 84306; - KEGG; hsa:84306; - UCSC; uc002nvj.4; human CTD; 84306; - GeneCards; PDCD2L; - HGNC; HGNC:28194; PDCD2L MIM; 615661; gene neXtProt; NX_Q9BRP1; - OpenTargets; ENSG00000126249; - PharmGKB; PA144596395; - eggNOG; KOG2061; Eukaryota eggNOG; ENOG410XRI4; LUCA GeneTree; ENSGT00530000063570; - HOGENOM; HOG000232160; - HOVERGEN; HBG060880; - InParanoid; Q9BRP1; - KO; K14801; - OMA; DLMRYEH; - OrthoDB; EOG091G0F9T; - PhylomeDB; Q9BRP1; - TreeFam; TF354282; - BioCyc; ZFISH:ENSG00000126249-MONOMER; - ChiTaRS; PDCD2L; human GenomeRNAi; 84306; - PRO; PR:Q9BRP1; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000126249; - CleanEx; HS_PDCD2L; - ExpressionAtlas; Q9BRP1; baseline and differential Genevisible; Q9BRP1; HS GO; GO:0005737; C:cytoplasm; IEA:InterPro GO; GO:0016020; C:membrane; IDA:UniProtKB GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW InterPro; IPR007320; PDCD2_C Pfam; PF04194; PDCD2_C; 1 1: Evidence at protein level; Acetylation; Cell cycle; Complete proteome; Phosphoprotein; Reference proteome INIT_MET 1 1 Removed. CHAIN 2 358 Programmed cell death protein 2-like /FTId=PRO_0000272645 MOD_RES 2 2 N-acetylalanine MOD_RES 20 20 Phosphoserine MOD_RES 22 22 Phosphothreonine SEQUENCE 358 AA; 39417 MW; 3946A6E4AD760155 CRC64; MAAVLKPVLL GLRDAPVHGS PTGPGAWTAS KLGGIPDALP TVAAPRPVCQ RCGQPLALVV QVYCPLEGSP FHRLLHVFAC ACPGCSTGGA RSWKVFRSQC LQVPEREAQD AQKQGNSLAA EDWCEGADDW GSDTEEGPSP QFTLDFGNDA SSAKDVDWTA RLQDLRLQDA VLGAAHPVPP GLPLFLPYYI CVADEDDYRD FVNLDHAHSL LRDYQQREGI AMDQLLSQSL PNDGDEKYEK TIIKSGDQTF YKFMKRIAAC QEQILRYSWS GEPLFLTCPT SEVTELPACS QCGGQRIFEF QLMPALVSML KSANLGLSVE FGTILVYTCE KSCWPPNHQT PMEEFCIIQE DPDELLFK
Research Areas
Citations (0)

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Background

MGC13096, also known as PDCD2L, might play a role in apoptosis given evidence that over expression attenutates TNF alpha release in Daudi cells anad restrained proliferation of HEK293T cells.

References

Chen, Q., et al. Hum. Immunol. 69 (4-5), 259-265 (2008) :Chen, Q., et al. Cell Biochem. Funct. 26(2):141-145(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Chen, Q., et al. Mol. Cell. Biochem. 280 (1-2), 185-191 (2005) :

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$ 80.00
Cat# BP19454c
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