|Other Names||Putative E3 ubiquitin-protein ligase UBR7, 632-, N-recognin-7, UBR7, C14orf130|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.|
|Tissue Location||Expressed in sperm (at protein level).|
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E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).
Lee, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(1):100-105(2008)Lim, J., et al. Cell 125(4):801-814(2006)
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