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NMD3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96D46
Clone Names 50908343
Peptide ID 50908343
Additional Information
Gene ID 51068
Other Names 60S ribosomal export protein NMD3, hNMD3, NMD3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1948b was selected from the C-term region of human NMD3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NMD3
Function Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
Cellular Location Cytoplasm. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner
Research Areas
Citations (0)

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It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.


Trotta, C.R., et al., EMBO J. 22(11):2841-2851 (2003).Ho, J.H. et al., Mol. Cell. Bio., 19(3):2389-2399 (1999).

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$ 80.00
Cat# BP1948b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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