Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.PLP2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Clone Names | 100324237 |
|---|---|
| Peptide ID | 100324237 |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
|---|---|
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an integral membrane protein thatlocalizes to the endoplasmic reticulum in colonic epithelial cells.The encoded protein can multimerize and may function as an ionchannel. A polymorphism in the promoter of this gene may be linkedto an increased risk of X-linked mental retardation. A pseudogeneof this gene is found on chromosome 5.
References
Zhang, L., et al. Genome Res. 17(5):641-648(2007)Lee, S.M., et al. Biochem. Biophys. Res. Commun. 324(2):768-772(2004)Wang, B., et al. J. Biol. Chem. 278(16):14461-14468(2003)Breitwieser, G.E., et al. Am. J. Physiol. 272 (3 PT 1), C957-C965 (1997) :Oliva, M.M., et al. Gene 159(2):151-157(1995)
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