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GABRR1 Antibody(N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P24046
Clone Names 100318093
Additional Information
Gene ID 2569
Other Names Gamma-aminobutyric acid receptor subunit rho-1, GABA(A) receptor subunit rho-1, GABA(C) receptor, GABRR1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GABRR1
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
Cellular Location Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Highly expressed in the retina and in a lesser extent in brain, lung and thymus
Research Areas
Citations (0)
citation

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Background

GABA is the major inhibitory neurotransmitter in themammalian brain where it acts at GABA receptors, which areligand-gated chloride channels. GABRR1 is a member of the rhosubunit family.

References

Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :Green, E.K., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2010) In press :Reyes-Ruiz, J.M., et al. Biochim. Biophys. Acta 1798(5):1002-1007(2010)Xuei, X., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (2), 418-427 (2010) :Kang, J.Q., et al. Trends Mol Med 15(9):430-438(2009)

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$ 277.78
Cat# BP19525a
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