|Other Names||Epidermal growth factor receptor kinase substrate 8-like protein 2, EPS8-like protein 2, Epidermal growth factor receptor pathway substrate 8-related protein 2, EPS8-related protein 2, EPS8L2, EPS8R2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.|
|Tissue Location||Detected in fibroblasts and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the EPS8 gene family. Theencoded protein, like other members of the family, is thought tolink growth factor stimulation to actin organization, generatingfunctional redundancy in the pathways that regulate actincytoskeletal remodeling.
Kim, J.E., et al. J. Proteome Res. 4(4):1339-1346(2005)Offenhauser, N., et al. Mol. Biol. Cell 15(1):91-98(2004)Tocchetti, A., et al. Genomics 81(2):234-244(2003)
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