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GSTT2 Antibody(Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P0CG29 |
|---|---|
| Clone Names | 90415102 |
| Gene ID | 2953 |
|---|---|
| Other Names | Glutathione S-transferase theta-2, GST class-theta-2, GSTT2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GSTT2 |
|---|---|
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:1417752). Has a sulfatase activity (PubMed:1417752). |
| Cellular Location | Cytoplasm, cytosol. Nucleus {ECO:0000250|UniProtKB:P30713} |
| Tissue Location | Expressed at low levels in liver. In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages and alveolar type II cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Glutathione S-transferase (GSTs) theta 2 (GSTT2) is amember of a superfamily of proteins that catalyze the conjugationof reduced glutathione to a variety of electrophilic andhydrophobic compounds. Human GSTs can be divided into five mainclasses: Alpha, Mu, Pi, Theta, and Zeta. The theta class membersGSTT1 and GSTT2 share 55% amino acid sequence identity and both arethought to have an important role in human carcinogenesis. Thetheta genes have a similar structure, being composed of five exonswith identical exon/intron boundaries.
References
Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(3):811-821(2010)Canova, C., et al. Tumori 96(1):1-10(2010)Wang, S., et al. Ann. Hum. Genet. 74(1):46-56(2010)Gemignani, F., et al. Mutat. Res. 671 (1-2), 76-83 (2009) :Tatemichi, M., et al. J. Hum. Genet. 54(10):557-563(2009)
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