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LTV1 Homolog Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96GA3
Clone Names 6022604
Additional Information
Gene ID 84946
Other Names Protein LTV1 homolog, LTV1, C6orf93
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1957c was selected from the Center region of human LTV1 Homolog. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LTV1
Synonyms C6orf93
Function Essential for ribosome biogenesis.
Cellular Location Cytoplasm. Note=The protein is expressed in a diffuse cytoplasmic pattern with granular perinuclear accentuation within the basal keratinocytes
Tissue Location Expressed in the epidermis.
Research Areas
Citations (0)
citation

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Background

In eukaryotes, 40S and 60S ribosomal subunits are assembled in the nucleus and exported to the cytoplasm independently of one another. Nuclear export of the 60S requires the adapter protein Nmd3, but no analogous adapter has been identified for the 40S. Ltv1 is a nonessential, nonribosomal protein that is required for 40S subunit biogenesis in yeast. A human LTV1 homolog has been identified but not fully characterized. It has been proposed that Ltv1 functions as one of several possible adapter proteins that link the nuclear export machinery to the 40S subunit.

References

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).

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$ 277.78
Cat# BP1957c
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Availability: 2 weeks
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