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TNNC2 Antibody(C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P02585 |
|---|---|
| Clone Names | 100324234 |
| Gene ID | 7125 |
|---|---|
| Other Names | Troponin C, skeletal muscle, TNNC2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TNNC2 |
|---|---|
| Function | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Troponin (Tn), a key protein complex in the regulation ofstriated muscle contraction, is composed of 3 subunits. The Tn-Isubunit inhibits actomyosin ATPase, the Tn-T subunit bindstropomyosin and Tn-C, while the Tn-C subunit binds calcium andovercomes the inhibitory action of the troponin complex on actinfilaments. The protein encoded by this gene is the Tn-C subunit.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Robinson, P., et al. FASEB J. 21(3):896-905(2007)Deloukas, P., et al. Nature 414(6866):865-871(2001)Vassylyev, D.G., et al. Proc. Natl. Acad. Sci. U.S.A. 95(9):4847-4852(1998)
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