|Other Names||Troponin C, skeletal muscle, TNNC2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Troponin (Tn), a key protein complex in the regulation ofstriated muscle contraction, is composed of 3 subunits. The Tn-Isubunit inhibits actomyosin ATPase, the Tn-T subunit bindstropomyosin and Tn-C, while the Tn-C subunit binds calcium andovercomes the inhibitory action of the troponin complex on actinfilaments. The protein encoded by this gene is the Tn-C subunit.
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Robinson, P., et al. FASEB J. 21(3):896-905(2007)Deloukas, P., et al. Nature 414(6866):865-871(2001)Vassylyev, D.G., et al. Proc. Natl. Acad. Sci. U.S.A. 95(9):4847-4852(1998)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.