|Other Names||Glucoside xylosyltransferase 2, 242n2, Glycosyltransferase 8 domain-containing protein 4, GXYLT2, GLT8D4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
GXYLT2 is a xylosyltransferase (EC 2.4.2.-) that adds thefirst xylose to O-glucose-modified residues in the epidermal growthfactor (EGF; MIM 131530) repeats of proteins such as NOTCH1 (MIM190198) (Sethi et al., 2010 [PubMed 19940119]).
Sethi, M.K., et al. J. Biol. Chem. 285(3):1582-1586(2010)
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