|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene catalyzes the breakdown ofmalonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is anintermediate in fatty acid biosynthesis, and also inhibits thetransport of fatty acyl CoAs into mitochondria. Consequently, theencoded protein acts to increase the rate of fatty acid oxidation.It is found in mitochondria, peroxisomes, and the cytoplasm.Mutations in this gene result in malonyl-CoA decarboyxlasedeficiency.
Sutendra, G., et al. Sci Transl Med 2 (44), 44RA58 (2010) :Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Yatscoff, M.A., et al. Pediatr. Res. 64(6):643-647(2008)Bouzakri, K., et al. Diabetes 57(6):1508-1516(2008)Salomons, G.S., et al. J. Inherit. Metab. Dis. 30(1):23-28(2007)
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