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Mouse Gnl3 Antibody(C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8CI11
Clone Names 110919131
Peptide ID 110919131
Additional Information
Gene ID 30877
Other Names Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, Gnl3, Ns
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Gnl3
Synonyms Ns
Function May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Cellular Location Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}
Tissue Location Expressed in the adult bone marrow population that is enriched in hematopoietic stem cells
Research Areas
Citations (0)

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Background

Gnl3 may be required to maintain the proliferative capacity of stem cells (By similarity).

References

Hirai, H., et al. Biochem. Biophys. Res. Commun. 391(1):299-304(2010)Tamase, A., et al. Proc. Natl. Acad. Sci. U.S.A. 106(40):17163-17168(2009)Nomura, J., et al. Stem Cells 27(5):1066-1076(2009)Ohmura, M., et al. Stem Cells 26(12):3237-3246(2008)Siddiqi, S., et al. Circ. Res. 103(1):89-97(2008)

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$ 80.00
Cat# BP19640b
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