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Mouse Gnl3 Antibody(C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8CI11 |
|---|---|
| Clone Names | 110919131 |
| Gene ID | 30877 |
|---|---|
| Other Names | Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, Gnl3, Ns |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Gnl3 |
|---|---|
| Synonyms | Ns |
| Function | May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. |
| Cellular Location | Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9} |
| Tissue Location | Expressed in the adult bone marrow population that is enriched in hematopoietic stem cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Gnl3 may be required to maintain the proliferative capacity of stem cells (By similarity).
References
Hirai, H., et al. Biochem. Biophys. Res. Commun. 391(1):299-304(2010)Tamase, A., et al. Proc. Natl. Acad. Sci. U.S.A. 106(40):17163-17168(2009)Nomura, J., et al. Stem Cells 27(5):1066-1076(2009)Ohmura, M., et al. Stem Cells 26(12):3237-3246(2008)Siddiqi, S., et al. Circ. Res. 103(1):89-97(2008)
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